Dragons trio Nick Tompkins, Elliot Dee and Aaron Wainwright all featured for Wales as England booked their place in the Autumn Nations Cup final with a 24-13 victory in Llanelli.
Wales opened the scoring with a runaway try from centre Johnny Williams before a score from Henry Slade and two Owen Farrell penalties gave the visitors a 11-7 half-time lead.
Mako Vunipola added a second-half try, while Farrell finished with 14 points.
For head coach Wayne Pivac it was a more encouraging display and Wales, who lost to Ireland before beating Georgia, currently lie in third place, and are likely to face Italy next weekend.
