Head Coach Rowland Phillips makes five changes to the starting line-up that defeated Hong Kong 65-0 last Friday.
Dragons trio Alicia McComish, Caryl Thomas and Bethan Lewis all start the game while Cerys Hale is named among the replacements.
A whole new front row of Thomas, Carys Phillips and Amy Evans start the game while there are also starts for Siwan Lillicrap and Keria Bevan.
Wales Women: Lauren Smyth (Ospreys), Jasmine Joyce (Scarlets), Alecs Donnovan (Ospreys), Alicia McComish (Dragons), Lisa Neumann (RGC), Robyn Wilkins (Blues), Keira Bevan (Ospreys); Caryl Thomas (Dragons), Carys Phillips (Ospreys), Amy Evans (Ospreys), Siwan Lillicap (Ospreys), Mel Clay (Ospreys), Manon Johnes (Blues), Bethan Lewis (Dragons), Sioned Harries (Scarlets)
Replacements: Kelsey Jones (Ospreys), Cara Hope (Ospreys), Cerys Hale (Dragons), Natalia John (Ospreys), Gwen Crabb (Ospreys), Ffion Lewis (Scarlets), Hannah Jones (Scarlets), Jess Kavanagh (RGC)